6分钟步行试验的运动强度和临床应用价值研究

Study on exercise intensity and clinical value of the six- minute walk test

目的:研究6分钟步行试验中的运动强度,并探讨其临床应用价值。方法:16名志愿者先进行6分钟步行试验(6MWT),测量每位受试者的6分钟步行距离(D)、做功(W)和结束时的摄氧量(VO2-6 MWT),再按Bruce方案进行极量心肺运动试验(CPET),检测每位受试者极量运动时的峰值摄氧量(VO2-peak)和无氧阈(AT),CPET和6 MWT均采用便携式K4 B2气体分析仪实时检测气体交换参数,以获得VO2-6 MWT、VO2-peak和AT。结果 :(1)6 MWT中16名受试者的摄氧量由运动初始的8.15 ml上升到28.42 ml,前1分钟上升较快,后5分钟基本进入平台期。(2)6分钟步行距离(6MWD)与6MWT结束时的摄氧量(VO2-6 MWT)成线性正相关;而VO2-6 MWT与CPET测得的AT无统计学差异。结论:对于健康受试者来说,6MWT是无氧阈水平的运动试验,它能够反映受试者日常生活活动能力,也可能反映其有氧运动能力。

Objective：To study the 6-minute walk test exercise intensity , and to explore its clinical value .Methods：16 volunteers re-ceived six-minute walk test （6MWT）, getting each subject＇s 6-minute walk distance （D）, acting （W） and VO2-6MWT.Subse-quently, subjects received cardiopulmonary exercise test （ CPET ） according to the Bruce protocol to detect peak oxygen uptake （VO2peak） and anaerobic threshold （AT）.The gas exchange parameters, such as VO2-6MWT, VO2-peak and AT, were detected by portable K4b2 real-time gas analyzer during 6MWT and CPET.Results：1.The average oxygen uptake of 16 subjects rose from 8.15ml at the test beginning to 28.42ml at the end of test during the 6MWT.The average oxygen uptake rose faster during the first minute , and came into platform during the last five minutes .2.Positive linear correlation was found between the 6-minute walk distance （6MWD） and VO2-6MWT.There was no significant difference between VO 2-6MWT and AT from CPET （p〉0.05）.Conclusion：6-minute walk-ing test shouls be an exercise test at level of anaerobic threshold for healthy subjects .6-minute walking test could reflect both submaximal exercise capacity and maximal exercise capacity .