期刊文献+

GnRH类似物对绝经前乳腺癌患者月经复潮影响的临床应用 被引量:1

下载PDF
导出
摘要 目的:观察GnRH类似物对绝经前乳腺癌需术后辅助化疗患者月经复潮的影响。方法:对确诊为乳腺癌并有维持正常月经要求的绝经前女性患者随机分为治疗组和对照组,比较2组患者化疗后的月经复潮情况。结果:24例绝经前乳腺癌患者均完成治疗,化疗后月经周期紊乱。治疗组、对照组复潮率分别为75%:50%,P<0.05,差异有统计学意义。结论:化疗可导致患者提前永久性闭经,化疗后的月经恢复情况与年龄相关。
出处 《中国伤残医学》 2014年第4期111-112,共2页 Chinese Journal of Trauma and Disability Medicine
  • 相关文献

参考文献6

二级参考文献21

  • 1Lu LUO Feng-chuan ZHU Yao-ying ZENG.The Mechanisms of Abnormal Bleeding in Patients with Anovulatory Dysfunctional Uterine Bleeding[J].Journal of Reproduction and Contraception,2002,13(4):222-230. 被引量:3
  • 2Huo, X,Hu, Z. B,Zhai, X. J,Wang, Y,Wang, S,Wang, X. C,Qin, J. W,Chen, W. S,Jin, G. F,Liu, J. Y,Gao, J,Wei, Q. Y,Wang, X. R,Shen, H. B.Common non-synonymous polymorphisms in the BRCA1 Associated RING Domain (BARD1) gene are associated with breast cancer susceptibility:a case-control analysis[J].南京医科大学学报(自然科学版),2007,27(7):743-743. 被引量:3
  • 3Mouridsen H, Gershanovieh M, Sun Y, et al. Superior efficacy of letrozole versus tamoxifen as first - line therapy for with advaneed breast cancer results of a phase Ⅲ study of the International Letrozole Breast Cancer Group [ J ]. J Clin Oneol,2001,19 ( 10 ) :2596 - 2606.
  • 4Baum M, Budzax AU, Cuzick J, et al. Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomized trial[J]. Lanctet,2002,359 (9324) :2131 - 2139.
  • 5Goss PE, Reid C, Pintilie M. Male breast carcinoma: A review of 229 patients who presented to the Princess Margaret Hospital during 40 years: 1955 - 1996 [ J ]. Cancer, 1999,85:629 - 639.
  • 6Ellis, Coop A, Singh B, et al. Letrozole inhibits tumor proliferation more effectively than tamoxifen independent of HER1/2 expression status[ J]. Cancer Res ,2003,63 ( 19 ) :6523 - 6531.
  • 7Eiermann W, Paepke S, Appfelstaedt J, et al. Preoperative treatment of postmenopansal breast cancer patients with letrozole: a randomized double - blind multicenter study [ J ]. Ann Oncol, 2001,12 ( 11 ) : 1527 - 1532.
  • 8Early Breast Cancer Trialists' Collaborative Group.Ovarian ablation in early breast cancer:overview of the randomised trials[J].Lancet,1996,348(9036):1189-1196.
  • 9Jonat W,Kaufmann M,Sauerbrei W,et al.Goserelin versus cyclophosphamide,methotrexate,and fl uorouracil as adjuvant therapy in premenopausal patients with node-positive breast cancer:The Zoladex Early Breast Cancer Research Association study[J].J Clin Oncol,2002,20(24):4628-4635.
  • 10Eisenhauer EA,Therasse P,BogaertsJ,et al.New response evaluation criteria in solid tumours:revised RECIST guideline(version 1.1)[J].EurJ Cancer,2009,45(2):228-247.

共引文献13

同被引文献6

引证文献1

二级引证文献12

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部