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间充质干细胞治疗心肌梗死研究进展 被引量：3

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摘要 2001年德国移植免疫和细胞治疗研究所 Strauer等首次对心肌梗死（MI）患者尝试自体骨髓干细胞移植,10周后发现患者左心室周长缩小,心脏指数、LVEF、心输出量等均有明显改善,坏死心肌的平均面积由24.6%减至15.7%.目前,虽未能广泛应用于临床治疗,但已能预见其广阔前景.
作者 陈各才 岳爱环 阮中宝 朱莉
机构地区 泰州市人民医院心内科 江苏省北科生物科技有限公司
出处 《中华老年心脑血管病杂志》 CAS 北大核心 2014年第1期98-99,共2页 Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
关键词 心肌梗死 间质干细胞 脐血干细胞移植 血管内皮生长因子类 肌细胞 心脏 细胞凋亡
分类号 R542.22 [医药卫生—心血管疾病]
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参考文献15

  • 1Psaltis PJ, Zannettino AC, Worthley SG, et al. Concise re view= mesenchymal stromal cells: potential for cardiovascular repair. Stem Cells,2008,26:2201 2210.
  • 2Uccelli A, Moretta L, Pistoia V. Mesenchymal stem cells in health and disease. Nat Rev Immunol, 2008,8:726-736.
  • 3Przybyt E, Harmsen MC. Mesenchymal stem cells: promising for myocardial regeneration? Curr Stem Cell Res Ther,2013, 8 : 270-277.
  • 4Ballard VL. Stem ceils for heart failure in the aging heart. Heart Fail Rev,2010,5:447 456.
  • 5Hodgkinsol CP, Gomez JA, Mrotsou M, et al. Genetic engi neering of mesenchymal stem cells and its application in hu man disease therapy. Hum Gene Ther,2010,21:1513 1526.
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同被引文献30

  • 1刘满江,胡雪松.心肌梗死的干细胞移植治疗新进展[J].中国医学文摘（内科学）,2006,27(4):308-310. 被引量：2
  • 2Narita T,Suzuki K. Bone marrow -derived mesenehymal stem cells for the treatment of heart failure[ J ]. Heart Fail Rev,2015,20( 1 ) :53 - 68.
  • 3Cai B,Wang G,Chen N, et al. Bone marrow mesenchymal stem cells protected post -infarcted myocardium against ar- rhythmias via reversing potassium channels remodelling[ J ]. J Cell Mol Med, 2014, 18(7): 1407-1416.
  • 4Daan K,Giltay EJ,Geleijnse JM. n-3 fatty acids and cardiovascularevents after myocardial infarction[J]. New Engl J Med,2015,363(21):2015-26.
  • 5Martin-Rendon E,Brunskill S,Doree C,et al. Stem cell treatment foracute myocardial infarction[J]. Cochrane Database of SystematicReviews,2014,40(2):74-84.
  • 6Zhang Q,Wang H,Yang YJ,et al. Atorvastatin treatment improves theeffects of mesenchymal stem cell transplantation on acute myocardialinfarction: the role of the RhoA/ROCK/ERK pathway[J]. Int J Cardiol,2014,176(3):670-9.
  • 7Kristensen SD,Laut KG,Jean F,et al. Reperfusion therapy for STelevation acute myocardial infarction 2010/2011: current status in 37ESC countries[J]. European Heart Journal,2014,35(29): 1957-70.
  • 8Ahmadi A,Soori H,Mehrabi Y,et al. Spatial analysis of myocardialinfarction in Iran: National report from the Iranian myocardialinfarction registry[J]. Clinical Journal of Pain, 2015, 20(5):446-55.
  • 9Bo L,Ole F,Olivecrona GK,et al. Outcomes 1 year after thrombusaspiration for myocardial infarction[J]. New England Journal of Medicine,2014,371(3):1111-20.
  • 10LI Zhuo GU Tian-xiang ZHANG Yu-hai.Hepatocyte growth factor combined with insulin like growth factor-1 improves expression of GATA-4 in mesenchymal stem cells cocultured with cardiomyocytes[J].Chinese Medical Journal,2008(4):336-340. 被引量：17

引证文献3

二级引证文献6

中华老年心脑血管病杂志
2014年 第1期

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