摘要
神经母细胞瘤(neuroblastma,NB)是儿童最常见的颅外实体肿瘤,多起源于肾上腺的神经嵴,由未分化的交感神经细胞组成,其中晚期神经母细胞瘤占60%左右,传统的治疗方法包括手术切除及放疗、化疗、骨髓根除治疗等,效果并不理想而且副作用大,其长期生存率仍然小于40%。
出处
《中华小儿外科杂志》
CSCD
北大核心
2014年第2期147-149,共3页
Chinese Journal of Pediatric Surgery
参考文献29
-
1Davidoff A M. Neuroblastoma[J].{H}Seminars in Pediatric Surgery,2012,(1):2-14.
-
2Jiang G,Xin Y,Zheng JN. Combining conditionally replicating adenovirus-mediated gene therapy with chemotherap:a novel antitumor approach[J].Int J Cancer,2011,(2):263-274.
-
3Bischoff JR,Kirn DH,Williams A. An adenovirus mutant that replicates selectively in p53-deficient human tumor cells[J].{H}SCIENCE,1996,(5286):373-376.
-
4Hallden G,Portella G. Oncolytic virotherapy with modified adenoviruses and novel therapeutic targets[J].{H}EXPERT OPINION ON THERAPEUTIC TARGETS,2012,(10):945-958.
-
5Garber K. China approves worlds first oncolytic virus therapy for cancer treatment[J].{H}JOURNAL OF THE NATIONAL CANCER INSTITUTE,2006,(5):298-300.
-
6Li Y,Zhang BF,Zhang HW. Oncolytic adenovirus armed with shRNA targeting MYCN gene inhibits neuroblastoma cell proliferation and in vivo xenograft tumor growth[J].{H}Journal of Cancer Research and Clinical Oncology,2013,(6):933-941.
-
7Geoerger B,van Beusechem VW,Opolon P. Expression of p53,or targeting towards EGFR,enhances the oncolytic potency of conditionally replicative adenovirus against neuroblastoma[J].{H}Journal of Gene Medicine,2005,(5):584-594.
-
8Adachi Y,Matsubara S,Muramatsu T. Midkine promoter-based adenoviral suicide gene therapy to midkine-positive pediatric tumor[J].{H}Journal of Pediatric Surgery,2002,(4):588-592.
-
9Van Maerken T,Sarkar D,Speleman F. Adenovirusmediated hPNPase (old-35) gene transfer as a therapeutic strategy for neuroblastoma[J].{H}Journal of Cellular Physiology,2009,(3):707-715.
-
10Pesonen S,Helin H,Nokisalmi P. Oncolytic adenovirus treatment of a patient with refractory neuroblastoma[J].{H}ACTA ONCOLOGICA,2010,(1):117-119.
二级参考文献6
-
1邵成浩,胡先贵,刘瑞,张怡杰,唐岩,曹贵松.血管内皮生长因子反义核酸对胰腺癌细胞增殖、凋亡和血管生成的影响[J].中华实验外科杂志,2006,23(1):18-20. 被引量:11
-
2高大新,冯继,姜永冲,王岩峰,李永军,温晓燕,李会民.血管内皮生长因子反义寡核苷酸对骨肉瘤细胞的抑制作用[J].中华实验外科杂志,2007,24(2):232-234. 被引量:1
-
3Suzuki A, Ito T, Kawano H,et al. Survivin initiates procaspaSe 3/p21 complex formation as a result of interaction with Cdk4 to resist Fasmediated cell death.Oncogene,2000,19:1346-1353.
-
4Pawan K,April I,Peter J,et al. p38 MAPK mediates γ-irradiation-induced endothelial cell apoptosis, and vascular endothelial growth factor protects endothelial cells through the phasphoinositide 3-kinase-Aktbcl-2 Pathway. J Bio Chem,2004,279:43352-43360.
-
5Zhang L,Yang N, Mohamed A, et al. Vector-based RNAi, a novel tool for isoform-specific knock-down of VEGF and anti-anglogenesis gene therapy of cancer. Biochem Biophys Res Commun, 2003,303 : 1169- 1178.
-
6沈为栋,李康华,郑晖,刘佑明.nm23和血管内皮生长因子表达及微血管密度与骨肉瘤转移的关系[J].中华实验外科杂志,2003,20(6):495-496. 被引量:3
同被引文献4
-
1邢莉莉,吴晔明.MYCN与神经母细胞瘤相关性研究进展[J].临床小儿外科杂志,2014,13(4):338-340. 被引量:4
-
2王振强,朱正纲.PDX模型在肿瘤转化医学中的应用与发展[J].中华胃肠外科杂志,2017,20(5):596-600. 被引量:7
-
3李雪(综述),黄利利(审阅),谢海燕(审阅).溶瘤病毒疗法的研究现状与展望[J].中国肿瘤生物治疗杂志,2020,27(5):559-565. 被引量:5
-
4宁小平(综述),虞淦军(综述),吴艳峰(审阅).溶瘤病毒的肿瘤临床应用研究进展[J].中国肿瘤生物治疗杂志,2020,27(6):705-710. 被引量:5
引证文献2
-
1李圆,朱孝宇,冯东川,禚保彪,龚金超,韩涛,张旭,郑骏年.携带白细胞介素-24基因的溶瘤腺病毒对裸鼠神经母细胞瘤的抗肿瘤作用[J].中华实验外科杂志,2017,34(12):2075-2077.
-
2陈晓彤,董瑞.溶瘤病毒在神经母细胞瘤治疗中的研究进展[J].中华小儿外科杂志,2022,43(2):175-180.
-
1徐一鹏,王华.溶瘤腺病毒治疗前列腺癌研究进展[J].中国肿瘤,2015,24(7):581-588. 被引量:1
-
2张子祥,李德春,赵华,朱东明.腹腔注射内皮抑素腺病毒治疗原位胰腺癌的实验研究[J].苏州大学学报(医学版),2009,29(1):17-20.
-
3孙柯科,姒健敏.幽门螺杆菌及其根除治疗与胃癌前病变[J].国外医学(消化系疾病分册),2004,24(2):74-77. 被引量:6
-
4杨春华,毛立军.间质干细胞荷载溶瘤腺病毒治疗肿瘤进展[J].中国肿瘤临床,2014,41(4):266-268.
-
5王华,李德川.溶瘤腺病毒治疗膀胱癌研究进展[J].中国肿瘤,2008,17(7):596-599.
-
6杨春华,毛立军.干细胞介导溶瘤腺病毒治疗脑胶质瘤研究进展[J].国际肿瘤学杂志,2011,38(11):833-835.
-
7徐立辉,蔡槱伯,王迪凡.基因工程腺病毒治疗裸鼠骨肉瘤肺转移的实验研究[J].中华肿瘤防治杂志,2009,16(14):1066-1068. 被引量:5
-
8王华,王宗平.膀胱癌溶瘤腺病毒治疗研究进展[J].中国肿瘤,2014,23(2):148-152. 被引量:1
-
9朱慧利,解平.胃镜下瘤内注射重组人p53腺病毒治疗晚期食道癌的安全性及短期疗效观察[J].实用医院临床杂志,2012,9(4):79-80. 被引量:8
-
10渠红霞,袁彩君,王越.吉西他滨联合溶瘤型腺病毒治疗大肠癌的体外研究[J].中国全科医学,2013,16(26):3088-3092. 被引量:2