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mTOR信号通路在儿童实体瘤中的研究概况

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摘要 哺乳动物雷帕霉素靶蛋白（mammaliantargetofrapam—ycin，roTOR）是一种丝／苏氨酸蛋白激酶，作为PT3K／Akt／mTOR信号转导途径中重要的信号分子，在调节细胞的增殖、生长、分化、凋亡、细胞周期调控、能量代谢等方面起着重要的作用。近年来研究发现，
作者 郑娜(综述) 李凯(审校)
机构地区 复旦大学附属儿科医院外科
出处 《中华小儿外科杂志》 CSCD 北大核心 2014年第2期150-152,共3页 Chinese Journal of Pediatric Surgery
关键词 mTOR 信号通路 实体瘤 雷帕霉素靶蛋白 苏氨酸蛋白激酶 儿童 信号转导途径 细胞周期调控
分类号 R542.2 [医药卫生—心血管疾病]
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参考文献28

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中华小儿外科杂志
2014年 第2期

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