静脉营养支持对早产儿体质量增长的临床效果分析

Analysis on the Clinical Effect of Intravenous Nutrition Support on Premature Low Birth Weight Infant

目的分析并评价静脉营养支持对早产儿体质量增长的临床效果与安全性。方法将湖南省儿童医院于2010年2月至2012年8月收治的963例不能耐受胃肠内营养的早产低体质量儿,依据应用静脉营养不同开始剂量的氨基酸分为两组:静脉营养组(482例)首次剂量为2.0 g/(kg·d),对照组(481例)首次剂量为0.5 g/(kg·d)。对比分析两组患儿体质量增长与各种并发症的发生情况。结果静脉营养组的日平均体质量增加量显著高于对照组,差异有统计学意义(P<0.05);两组患儿生存率、病死率及住院天数相比差异均有统计学意义(P<0.05);两组患儿并发症发生率比较差异无统计学意义(P>0.05)。结论静脉营养支持能有效改善早产儿的营养状况,更好地增加体质量,且不良反应少,提倡临床推广应用。

Objective To analyze and evaluate the clinical effect and safety of intravenous nutrition sup- port on body weight increase of premature infants. Methods From Feb. 2010 to Aut. 2012, Hunan Children＇s Hospital treated 963 premature and low birth weight infants of intolerance to enteral nutrition were divided into intravenous nutrition group（482 cases） with the first close of 2.0 g/（ kg · d）, and the control group （481 cases） with the first close of 0.5 g/（ kg · d） , and the weight gain and various complications oc- currence of the two groups were comparatively ana]yzed. Results The intravenous nutrition group average daily weight gain was significantly higher than the control group （ P 〈 0.05 ） ; the survival rate, mortality and hospital stay of the two groups were significantly different（ P 〈0. 05 ） ; the complications incidence of the two groups was not significantly different （ P 〉 0.05 ）. Conclusion Intravenous nutrition support can improve the nutrition status of infants, better gain weight,with less untoward reaction, thus the clinical application should be promoted.