均匀设计法优化藏药蔓菁膏提取工艺的研究

Optimization on Extraction Process of Brassicae Radix Cream by Uniform Design

目的:优化藏药蔓菁膏煎煮法的提取工艺。方法:采用均匀设计法和综合评分法,以出膏率、总多糖含量为评价指标,对藏药蔓菁膏煎煮法的提取工艺参数进行优化。结果:藏药蔓菁膏煎煮法的提取工艺优化条件为:加水10倍量,煎煮4次,每次1 h。结论:该提取工艺稳定、可行,为藏医临床及生产制备蔓菁膏提供实验依据。

This study was aimed to find out the optimum parameters to decoction extraction process of Brassicae Radix cream . With methods of integrated score and uniform design , contents of the total extract and the total polysaccharide were set as the target to investigate the optimization process of extraction. The experiment showed that the optimum extraction condition was as follows： ten folds of water, four times decoction at boiling tempera-ture , one hour for each time . It was concluded that the optimum parameters to decoction extraction of Brassicae Radix were stable and feasible, which can be used for the preparation and reference for Brassicae Radix cream in Tibetan clinics .