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嗜酸性粒细胞性胃肠炎临床特点分析 被引量:9

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摘要 目的探讨嗜酸性粒细胞性胃肠炎(EG)的临床特征。方法对21例EG患者的临床资料进行回顾性分析。结果 21例EG患者中,最常见的临床症状为腹痛(76.2%),以及恶心呕吐、腹胀、腹泻、纳差等。20例外周血嗜酸性粒细胞增高(95.2%),内镜检查见炎症最常累及胃窦及十二指肠球部,组织活检可见嗜酸性粒细胞浸润。黏膜型13例,混合型(黏膜型合并浆膜型)8例。腹腔积液阳性者(7例),混合型所占比例、合并电解质紊乱例数及CRP水平均高于腹腔积液阴性者(14例)。21例确诊后均予饮食调节和去除过敏原治疗,同时给予抑酸、保护胃黏膜、调节胃肠动力和肠道菌群等药物,其中15例予泼尼松治疗。治疗后患者嗜酸性粒细胞计数低于治疗前,症状得到改善。结论 EG临床表现无特异性,超敏反应病史、外周血嗜酸性粒细胞计数增高、胃肠道组织嗜酸性粒细胞浸润有助于诊断,确诊依靠组织活检。合并腹腔积液者较无腹腔积液者病情重。治疗主要是去除过敏原及对症治疗,对于症状较重者可加用糖皮质激素。
机构地区 天津市南开医院
出处 《山东医药》 CAS 2014年第2期70-72,共3页 Shandong Medical Journal
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共引文献87

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