桐乡市常见恶性肿瘤危险因素分析

An Analysis on Risk Factors of Common Malignant Tumors in Tongxiang City

目的了解桐乡市常见恶性肿瘤的危险因素。方法收集桐乡市恶性肿瘤1 154例,采用多病例组1∶1匹配的病例对照研究方法,利用多因素非条件Logistic回归模型分析桐乡市常见恶性肿瘤的危险因素。结果精神长期处于压抑状态或者经历精神创伤与肺癌、结直肠癌、肝癌、胃癌和乳腺癌的发病相关(OR=3.590、3.923、3.896、12.429和11.291)。肺癌、胃癌、结直肠癌和肝癌的共同危险因素有相关疾病史和肿瘤家族史。饮茶和多吃新鲜水果蔬菜是肺癌的保护因素(OR=0.569和3.161),而吸烟是肺癌和胃癌的危险因素(OR=3.826和5.699)。饮酒为结直肠癌和肝癌的危险因素(OR=3.593和5.316),而少吃烟熏食品则有利于预防结直肠癌的发生(OR=0.093)。结论吸烟、饮酒、饮食等生活方式,精神、心理因素、疾病史和肿瘤家族史等为桐乡市常见恶性肿瘤的危险因素。

Objective To explore the risk factors of common malignant tumors in Tongxiang City.Methods A total of 1 1 54 malignant tumor cases were collected and multi-case group was built.The design method of 1 to 1 matching case-control study was used.The data was analyzed by multiple-factor non-conditional Logistic regression analysis.Results Long term depressed state or psychic trauma was the risk factor of 5 common malignant tumors including lung cancer, colorectal cancer,liver cancer,gastric cancer and breast cancer （OR =3.590,3.923,3.896,1 2.429 and 1 1.291 respectively）.The common risk factors relating to lung cancer,gastric cancer and colorectal cancer were diseases history （OR=2.81 7,7.799 and 7.650）and family history of cancer（OR=3.674,6.594 and 1 1.954）.Drinking tea and eating more fresh fruits and vegetables were protective factors of lung cancer（OR=0.569 and 3.1 61 ）,but smoking was a risk factor for lung cancer and gastric cancer（OR=3.826 and 5.699）.Alcohol drinking was the risk factor for both colorectal cancer and liver cancer（OR=3.593 and 5.31 6）,eating less smoked foods may help prevent the occurrence of colorectal cancer（OR=0.093）.Conclusion Lifestyles like smoking,drinking,dietary habits,spiritual and psychological factors, disease history and family history of cancer are the risk factors of common malignant tumors in Tongxiang city.