头颈部嗜酸性淋巴肉芽肿14例临床分析

The clinical study of eosinophilic lymphogranuloma patients:fourteen cases analysis

目的 探讨头颈部嗜酸性淋巴肉芽肿（ELG）的临床特点,以提高临床诊治水平。方法 回顾性分析中山大学孙逸仙纪念医院口腔颌面外科2003 - 2012年14例头颈部ELG的临床资料,分别从研究对象的发病年龄、性别、发病部位、实验室检查、病理、临床表现、治疗及预后等方面进行总结。结果 所有病例均经病理检查确诊。治疗后随访时间为1 ~ 13个月,其中1例经肿块切除术,术后5个月复发;1例经药物治疗,治疗后4个月复发。其余12例患者预后良好,随访期间未出现病情进展或复发。结论 ELG常表现为一种无痛的软组织病变,好发于男性,多见于中青年人,好发部位为腮腺区、颈部等。主要依靠病理确诊,最佳治疗方案是手术切除结合适当剂量的放疗。

Objective The purpose of this study was to summarize the clinical features of the head and neck eosinophilic lymphogranuloma（ELG） for clinical application. Methods Through a retrospective analysis of clinical data of 14 ELG patients in our department from 2003 to 2012, we analyzed their clinical data which including patients＇ age, sex, extent of lesion, laboratory tests, pathology, clinical features, treatment and prognosis. Results All cases were confirmed by pathological examination. Follow-up time was between 1 ~ 13 months. 1 case with tumor recurrence 5 months postoperative; 1 case with drug therapy recurrent 4 months after treatment. No local recurrence and no progression to eosinophilic lymphogranuloma（ELG） has been reported in the remaining 12 cases within the follow up period. Conclusions ELG is a kind of painless soft-tissue mass and commonly occurs in the male, especially in the young. The most common site is parotid region. Its diagnosis mainly relies on pathological findings. The optional treatment of ELG is surgical combined with an appropriate dose of radiotherapy.