多囊卵巢综合征与致密性髂骨炎相关性的临床研究

Analysis on correlation between Polycystic ovary syndrome and Osteitis condensans ilii

目的探讨多囊卵巢综合征与致密性髂骨炎的关系。方法连续收集本中心2012年7月至2012年11月558例行子宫输卵管造影(HSG)的不孕症患者,并排除有干扰性因素的患者如肥胖、结核和风湿等。临床诊断为多囊卵巢综合征(Polycystic ovary syndrome,PCOS)为A组,余下为B组。观察两组不孕症患者罹患致密性髂骨炎(Osteitis condensans ilii,OCI)的情况。结果患有多囊卵巢综合征A组230例,造影过程中表现为典型致密性髂骨炎X线特点的患者有53(23.04%)例,其中仅有两例为单侧髂骨耳状关节部分骨质密度增高。无PCOS的B组328例,造影过程中表现为典型致密性髂骨炎X线特点的患者有16(4.88%)例,均为双侧髂骨耳状关节部分骨质密度增高。多囊卵巢综合征患者患有致密性髂骨炎的几率明显高于B组,差异有统计学意义(P<0.05)。结论多囊卵巢综合征患者自身代谢内分泌的紊乱可能对骨代谢产生一定影响。

Objective To investigate the relationship between Polycystic ovary syndrome （PCOS） and Osteitis condensans ilii（OCI）. Methods Continuous collection 558 infertile women in our Reproductive center that inspected with hysterosalpingography from July 2012 to November 2012 and excluded the patients with disruptive factors such as obesity, tuberculosis and rheumatism. Clinical diagnosis of Polycystic ovary syndrome （PCOS） for group A, the rest of group B. Observe two groups of infertility patients suffering from OCI. Results A group of 230 cases of patients with polycystic ovary syndrome, imaging process characterized by OCI typical X-ray characteristics of patients in 53 （23.04%） cases and only two cases of unilateral iliac auricular joint part increased bone density. For group B without PCOS, a total of 328 cases, imaging process characterized by compactness iliac phlogistic typical patients with X-ray features of 16 cases （4.88 % ）, all of them are bilateral iliac auricular joint part increased bone density. Polycystic ovary syndrome patients suffering from inflammation of compactness iliac chance is significantly higher than group B（P〈0.05）. Conclusion Patients with PCOS, metabolic endocrine disorders may have an impact on bone metabolism.