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Fe^(2+)在青蒿素类药物药理机制中作用的研究进展

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摘要 青蒿素是我国科学家从植物中提取的新一代抗疟疾药物,近年来大量研究发现青蒿素类药物除了具有抗疟疾作用外,还具有抗肿瘤、抗血吸虫、抗结核等多方面的药理作用,但其药理机制却不全明确。大量研究证实Fe2+在青蒿素类药物的药理机制中起到了关键作用,深层次研究Fe2+是如何在青蒿素类药物的药理机制中发挥作用,对于进一步揭示青蒿素类药物的药理作用机制及寻找其可能靶点有重要意义。
作者 程琪 王利民
机构地区 泸州医学院临床医学院 四川绵阳四〇四医院 川北医学院第二附属医院呼吸与危重症医学科
出处 《青岛医药卫生》 2014年第1期53-56,共4页 Qingdao Medical Journal
基金 四川省卫生厅科研基金资助项目(080223)
关键词 FE^2+ 青蒿素类药物 疟疾 肿瘤 血吸虫 结核 机制
分类号 R96 [医药卫生—药理学]
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参考文献45

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青岛医药卫生
2014年 第1期

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