超敏C反应蛋白、心肌肌钙蛋白I和血乳酸在急性病毒性心肌炎中的诊断价值

Diagnostic value of hs-CRP, cTnI, and blood lactic acid for acute viral myocarditis

目的研究超敏C反应蛋白(hs-CRP)、心肌肌钙蛋白I(cTnI)和血乳酸(LAC)三项指标联合检测在急性病毒性心肌炎(AVM)诊断中的价值。方法动态监测54例AVM患者的hs-CRP、cTnI和LAC的水平变化,并与正常对照组相比较。结果三项指标的水平均随着患者入院时间延长而逐渐升高。其中,hs-CRP水平入院后0h即升高,阳性率达96.3%,并逐步升高,入院后24h达高峰,后逐步下降。而cTnI和LAC水平分别于患者入院后12h和24h升高。结论 hs-CRP、cTnI和LAC三项指标的联合检测有助于AMI的早期诊断,值得在临床上推广应用。

Objective To investigate the diagnostic value of high-sensitivity C-reactive protein （hs-CRP）, cardiac troponin I （cTnI）, and blood lactic acid （Lac） combined for acute viral myocarditis （AVM）. Methods Fifty-four AVM patients were dynamically monitored for hs-CRP, cTnI, and Lac levels and compared with the normal control group in terms of these indices. Results The three indices increased gradually in these patients during hospitalization. The hs-CRP level began to rise immediately after hospitalization, with a positive rate of 96.3%, and it reached the peak at 24 h after admission and then fell gradually; the cTnI and Lac levels were elevated at 12 h and 24 h, respectively, after admission. Conclusion Joint measurement of hs-CRP, cTnI, and Lac is helpful for the early diagnosis of AMI and holds promise for clinical application.