卡托普利治疗稳定劳力型心绞痛的临床效果

Clinical efficacy of captopril in treatment of stable exertional angina pectoris

目的：卡托普利在治疗稳定性劳力型心绞痛在临床治疗中的效果分析。方法选取2005年3月～2012年10月来我院进行治疗的稳定性劳力型心绞痛患者共200例，年龄为53～72岁，并随机分成两组观察组与对照组，每组各100例。对照组与观察组分别采用常规的治疗方法以及在常规治疗方法的基础上施以卡托普利治疗。其中，常规的治疗方法主要是采用β-受体阻滞剂，阿司匹林，硝酸酯类以及钙拮抗剂进行治疗。对两组的治疗情况进行观察与分析。结果在经过一段时间的临床应用治疗之后，观察组与对照组的稳定性劳力性心绞痛的治疗效果有着明显的改善，但是观察组的治疗效果明显优于对照组，观察组与对照组见的心率明显不一样，观察组慢于对照组。并且在运动过程中观察组的心绞痛病症诱发时间明显长于对照组。结论卡托普利在治疗稳定劳力型心绞痛病症的过程中有着显著的疗效，具有重要的临床意义。

Objective To analyze the clinical efficacy of captopril in the treatment of stable exertional angina pectoris. Methods A total of 100 patients with stable exertional angina pectoris （mean age 53-72 years）, who were treated in our hospital from March 2005 to October 2012, were selected as subjects and randomly divided into observation group and control group. The control group received conventional treatment （β-blockers, aspirin, nitrate, and calcium antagonists）, while the observation group received captopril in addition to conventional treatment. The treatment outcomes of the two groups were observed and analyzed. Results After a certain course of clinical treatment, both groups showed significant improvements, but the treatment outcome was significantly better in the observation group than in the control group; the observation group had a significantly lower heart rate than the control group. In addition, the observation group had a significantly longer angina pectoris induction time during exercise compared with the control group. Conclusion Captopril has significant efficacy in the treatment of stable exertional angina pectoris and is of great clinical significance.