基于电-机复合机制实现胃动力学的检测与评价

Gastric motility measurement and evaluation based on electrical-mechanical composite mechanism

胃的运动和排空是一个复杂的电活动-机械收缩和传导的过程,胃动力学研究应该基于电-机复合机制的认识高度,将电活动和由其引发的胃机械收缩与传导紧密联系.相关模拟与临床实验研究表明,电阻抗胃运动信号与胃电图(electrogastrogram,EGG)检测结合,以EGG作为胃起搏生理时标,由多通道电阻抗信号提取胃的运动状态,依据EGG活动与机械收缩的偶联,进行多源信号相关分析,深入探讨胃传导性收缩的幅度、时限、方向以及传导距离等因素的影响,可建立有效的胃动力功能无损伤检测和评价新方法,实现基于胃动力电-机复合机制的胃动力学研究.

Gastric motility and emptying are a composite course involving electrical activity and me- chanical contraction. In the research of gastric motility, the electrical activity should be closely connected to the subsequent mechanical contrac- tion based on the understanding of electrical- mechanical composite mechanism. Existing simulation research and clinical research suggest that electrogastrogram （EGG） signals can pro- vide physiological time scales, and gastric mo- tility can be extracted from impedance signals. According to the coupling of the myoelectric activity and the mechanical contraction of the stomach, the correlation analysis of multiple sig- nals can be performed. And then the influence of various factors such as the range, time and transmission distance of the ~astric contractioncan be deeply explored. The method combining gastric impedance and synchronous EGG mea- surements is effective and promising for evalu- ating gastric motility.