两种亚型FD患者的口盲传递时间

Assessment of orocecal transit time by breath hydrogen test in two subtypes of functional dyspepsia

目的:研究两种亚型功能性消化不良(functional d y s p e p s i a,F D)患者的口盲传递时间,探讨性别、年龄、体质量指数(body mass index,BMI)对口盲传递时间的影响.方法:对25例餐后不适综合征(postprandial distress syndrome,PDS)患者、22例上腹痛综合征(epigastric pain syndrome,EPS)患者及20例健康对照者进行氢呼吸实验,记录口盲传递时间(orocecal transit time,OCTT).结果:(1)PDS组的OCTT较健康组明显延长,而EPS组与健康组无显著差异;(2)三个实验组中,不同性别之间的OCTT均无显著差异;(3)健康组中,年龄与OCTT呈正相关,PDS组及EPS组中无该相关性;(4)健康组中,BMI与OCTT呈正相关;PDS组及EPS组中无该相关性.结论:PDS患者的小肠传输功能明显下降;年龄及BMI对健康人的OCTT有一定影响,而对PDS患者及EPS患者无显著影响.

healthy volunteers. Gender appeared not to influence OCTT in all three groups. There was a positive correlation between age and OCTT in healthy volunteers, but not in PDS patients or EPS patients. BMI-related differences in OCTT were noted in healthy volunteers, but not in PDS patients or EPS patients. CONCLUSION： In PDS patients, intestinal tran- sit function is impaired. Age and BMI appear to influence OCTT in healthy volunteers, but not in PDS patients or EPS patients.