ELP与FAM方案治疗胃癌的临床疗效比较

CLINICAL CURATIVE EFFECT OF THE STOMACH IS FAM AND ELP TREATMENT SCHEME ON CANCER

目的:观察ELP方案与FAM方案治疗胃癌的临床疗效。方法:将300例胃癌患者,随机分为两组,治疗组150例,用ELP方案进行化疗。对照组150例,用FAM方案进行化疗。两组均给予对症,支持等治疗,总疗程为半年,观察疗效,起效时间及不良反应。结果:治疗组的总有效率为(75%)高于对照组(61%)(P<0.01),治疗组起效时间明显缩短(P<0.05),化疗后治疗组的症状改善率为80%,对照组为57%。两组均有恶心,呕吐,脱发,白细胞减少,肝肾功能损害等不良反应,治疗组发生率为46%,对照组为55%。结论:ELP方案治疗胃癌有效率高于FAM方案,不良反应低于FAM方案,值得临床治疗应用。

Objective：Observe the clinical curative effect of gastric cancer treatment with. ELP plan and FAM scheme Methods： 300 cases of gastric cancer patients were randomly divided into two groups. The treatment group 150 examples were doctoved with the ELP scheme of chemotherapy and 150 patients in control with FAM scheme of chemotherapy. Both groups were given symptomatic and support treatment, the total period of which was half a year in orderto observe curative effect, work time and adverse reaction. Results： The total effective rate of the treatment group（75% ） was higher than that in the control group （61%） （P 〈0. O1 ）, the treatment group work time significantly shortened（P 〈 O. 05）. After chemotherapy treatment group had the impravement nate for 80% and the placebo group 57%. Both groups have nausea, vomiting, loss of hair, leukopenia, liver and kidney function adverse reactions as dam- age, the treatment group was 46%, and in the placebo group 55%. Conclusion： efficieny of ELPscheme treatment on stomach FAM higher than scheme and its adverse reaction FAM acheme, and ,the clinical application.