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重型颅脑外伤并脓毒血症患者的血清TF、TFPI、hs-CRP变化及意义 被引量:8

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摘要 目的 探讨重型颅脑外伤并脓毒血症患者的血清组织因子途径抑制物(TFPI)、组织因子(TF)和高敏C反应蛋白(hs-CRP)变化及临床意义.方法 选择重型颅脑外伤并脓毒血症患者33例(观察组),同期健康献血员15例(对照组),采用ELISA法检测观察组感染早期(外伤后3d内)、中晚期(外伤后3~7d)血清TFPI、TF、hs-CRP,对照组在查体时检测上述指标.结果 与对照组比较,观察组感染早期TFPI、TF及hs-CRP明显升高,感染中晚期TF、hs-CRP升高(P均<0.01);与感染早期比较,感染中晚期TF、hs-CRP升高,TFPI降低(P均<0.05).结论 重型颅脑外伤并脓毒血症患者血清TF、TFPI及hs-CRP动态变化可作为脓毒血症病情变化的监测指标.
出处 《山东医药》 CAS 2014年第5期39-40,共2页 Shandong Medical Journal
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参考文献13

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