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石棉致癌的调查研究 被引量:6

AN INVESTIGATION ON ASBESTOS INDUCED MALIGNANT TUMOUR
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摘要 近年来,作者对石棉厂、矿和两个青石棉区共25,314例工人、农民所发生的恶性肿瘤进行了调查。结果表明,石棉工人肺癌高发,接触青石棉的人群恶性间皮瘤显著增高(P<0.01),死于石棉肺合并肺癌为14.8~17.4%,与国外15~20%的范围一致。石棉工人消化道癌国外报道有显著增高,而本文未见高发,这需要追踪观察。石棉与其它癌尤其是喉癌的关系国外多有报道,本文调查结果喉癌和其它癌虽有发生,但与石棉接触尚未见显著关系。 17618 chrysotile exposed workers and 7696 farmers living in crocidolite area were investigated on asbestos induced malignant tumour. The local population was taken as the controls for workers, while the farmers living in nearby area without crocidolite contamination were taken as the control group for the latter. The findings showed that the pattern of malignancy mortality in workers group was significantly different from that of the general population group (P<0.1) , but no difference was found in farmer groups. The lung cancer was significantly higher in both workers and farmers than that of the control groups. The mesothelioma occuring in farmers living in crocidolite area was significantly higher than that of the control group (P<0.01) . The rate of death in asbestosis complicated with lung cancer was 14.8-17.4%, about the same with tie result reported by others. The incidence of gastrointestinal cancer neither in workers nor in farmers was higher than those of their control group.
机构地区 华西医科大学
出处 《工业卫生与职业病》 CAS CSCD 1991年第3期149-152,共4页 Industrial Health and Occupational Diseases
关键词 肺癌 消化道癌 石棉纤维 Asbestos fibre lung cancer mesothelioma gastrointestinal cancer
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同被引文献22

  • 1张华强,张忠群,王元林.接触石棉工人胃癌死亡回顾性队列研究[J].中国工业医学杂志,1996,9(6):358-359. 被引量:1
  • 2周凯辉,刘萍,玄春山,赵玉洁.石棉工人恶性肿瘤24年追踪研究[J].中国公共卫生,1996,12(11):515-516. 被引量:4
  • 3王治明 曹永芳 等.石棉和肺癌[J].中华劳动卫生职业病杂志,1988,6(1):6-6.
  • 4董德甫,关黎威,王秀清.鞍钢焦炉工人肺癌进一步研究[J].工业卫生与职业病,1990,16(6):334-339. 被引量:7
  • 5IPCS. Chrysotile asbestos. Environmental Health Criteria 203 [ C ].Geneva: World Health Organization, 1998.
  • 6SMITH A H, WRIGHT C C. Chrysotile asbestos is the main cause of pleural mesothelioma [J]. Am J Ind Med, 1996, 30(3) :252 -266.
  • 7VALIC F. The asbestos dilemma: Ⅰ. Assessment of risk [J]. Arh Hig Rada Toksikol, 2002, 53(2):153-167.
  • 8MCDONALD J C. Unfinished business: the asbestos textile mystery[J]. Ann Occup Hyg, 1998, 42(1):3 -5.
  • 9FRUMKIN H, BERLIN J. Asbestos exposure and gastrointestinal malignancy review and mata-analysis [J]. Am J Ind Med, 1988, 14( 1 ) :79 - 95.
  • 10GOODMAN M, MORGAN R W, RAY R, et al. Cancer in asbestosexposed occupational cohorts: a meta-analysis [ J]. Cancer Cause Control, 1999, 10(5) : 453 -465.

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