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肿瘤坏死因子拮抗剂治疗类风湿关节炎的研究进展 被引量：2

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摘要 类风湿关节炎（RA）是一种以慢性骨侵蚀性为主要表现的系统性自身免疫性疾病.滑膜的慢性炎症导致关节破坏和畸形、功能渐进性障碍,随之而来的是患者生活质量降低和死亡率上升.RA患者致残率可达30%,死亡率增加至52%,另外还会导致感染和心血管等疾病的发生[1].治疗RA目的就是为了缓解病情的活动性,预防和控制关节破坏,减少其他严重的合并症,如心脏病和脑卒中等.早期干预对RA患者改善关节功能显得尤为重要.
作者 马喜喜 徐胜前
机构地区 安徽医科大学第一附属医院风湿免疫科
出处 《临床内科杂志》 CAS 2014年第1期68-70,共3页 Journal of Clinical Internal Medicine
关键词 类风湿关节炎 治疗 肿瘤坏死因子拮抗剂
分类号 R593.22 [医药卫生—内科学]
  • 相关文献

参考文献31

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二级参考文献22

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共引文献95

同被引文献52

  • 1李军,张奉春.糖皮质激素在类风湿关节炎中的应用[J].中国医刊,2004,39(8):11-13. 被引量：3
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二级引证文献11

临床内科杂志
2014年 第1期

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