嗜酸性胃肠炎2例临床分析

Clinical analysis of childhood eosinophilic gastroenteritis in two cases

目的探讨嗜酸性胃肠炎的临床特点。方法回顾性分析2例嗜酸性胃肠炎患儿的临床资料。结果 2例患儿均有外周血嗜酸性粒细胞明显增高,肠黏膜病理检测示嗜酸粒细胞浸润,经低敏膳食和氨基酸配方粉喂养及抗过敏治疗,症状即明显好转。结论嗜酸性胃肠炎以嗜酸性粒细胞浸润为其主要特征,致病因素不明确,治疗缺乏循证医学依据。

Objective To explore the clinical characteristics of eosinophilic gastroenteritis. Methods The clinical data of 2 children with eosinophilic gastroenteritis was retrospectively analyzed. Results Eosinophilia was found in both cases and path-ological examination indicated eosinophil infiltration in intestinal mucosa. The clinical symptoms were improved after hypoaller-genic diet, amino acid formula and anti-allergy treatment. Conclusions Eosinophilic gastroenteritis is characterized by eosino-phil infiltration with unknown pathogenic factor leading the treatment of eosinophilic gastroenteritis lacking of sound evidence.