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HPV相关头颈部肿瘤分子表型及对放化疗敏感性的影响 被引量:1

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摘要 人乳头瘤病毒(human papillomavirus,HPV)相关头颈部肿瘤,特别是口咽癌,作为独特的群体被广泛认可。其良好预后与放化疗敏感性的提高密不可分,然而,影响HPV相关肿瘤放化疗敏感性的分子机制尚不明确。本文从HPV相关头颈部肿瘤特殊的基因型和分子生物学特征入手,收集国际上HPV相关分子生物学方面的研究成果,以现有的影响放化疗敏感性的理论为依据,筛选、提炼潜在分子指标和信号通路,以期为HPV相关头颈部肿瘤放化疗敏感性研究提供线索。
出处 《癌症进展》 2014年第1期54-58,共5页 Oncology Progress
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