B超引导下乳腺肿块粗针穿刺诊断的分析(附120例报道)

Analysis of 120 Cases Ultrasonic Guidance Core Needle Aspiration Biopsy Diagnosis to Breast Masses

目的:探讨B超引导下粗针穿刺在乳腺肿块诊断中的应用意义。方法:使用B超引导下粗针吸取穿刺对120例乳腺肿块进行穿刺活检,然后进行固定,脱水,染色,镜检,结合临床作出病理学诊断。结果:粗针穿刺诊断包括良性病变48例,非典型性导管上皮增生(ADH)32例,导管内癌12例,浸润性癌28例。与后续手术标本病理诊断比较得出确诊率,其中良性病变的诊断率为95.83%(46/48),ADH的确诊率为75%(24/32),导管内癌的确诊率为58.33%(7/12),浸润性癌诊断率为92.86%(26/28),其中导管内癌与浸润性导管癌和乳腺良性病变的确诊率有显著性差异,而ADH与浸润性导管癌和乳腺良性病变间的确诊率有差异,但本组数据没有统计学意义。结论:超声引导下粗针穿刺对乳腺浸润性癌和良性病变的诊断率较高,但对ADH和原位癌的确诊率较低,有待进一步改进。

Objective： The purpose of this study was to evaluate significance of ultrasonic guided core needle biopsy application into breast masses. Methods： We retrospectively reviewed the pathologic results of ultrasonic guided core needle biopsy of solid breast masses. A total of 120 breast masses diagnosed with this procedure and surgically excised were included in the study, then they were taken fixation, dehydration, staining, microscopic observation, ultimately pathological diagnosis. Results： Compared to the results of surgical excision of 120 breast masses , the diagnosis rates by ultrasonic guided core needle biopsy were 95.83% （46/48） for benign lesions, 75% （24/32）for atypical ductal hyperplasia （ADH）, 58.33% （7/12）for Intraductal carcinoma, 92.86% （26/28） for infiltrating cancer, and statistically significant differences were found between Intraductal carcinoma and infiltrating cancer or benign lesions; differences were found between ADH and infiltrating cancer or benign lesions, but no statistically significant. Conclusions： Higher diagnostic rate by ultrasonic guided core needle biopsy was for infiltrating cancer and benign lesion than for Intraductal carcinoma and ADH, so it is necessary to improve it.