便携式紫外光治疗仪治疗白癜风34例临床观察

Efficacy of Portable Therapeutic UV Instrument in the Treatment of Vitiligo

目的观察便携式紫外光(UV)治疗仪对白癜风的临床疗效,为白癜风的家庭UV治疗提供更多的理论依据。方法收集本院2010年1月-2011年12月期间皮肤科收治的白癜风患者68例,随机分成2组:常规UV治疗组(A组,n=34)和便携式UV治疗组(B组,n=34),观察两组的临床疗效。结果 A组和B组的临床治疗有效率分别为52.94%和55.88%,两组之间差异无统计学意义(P>0.05);A,B两组的临床疗效在不同部位皮损之间差异无统计学意义(P>0.05)。在4个疗程结束时A,B两组的临床疗效显著高于2个疗程结束时,疗程结束后A,B两组的色素评分均较治疗前显著升高,差异均有统计学意义(P均<0.01)。结论便携式紫外光治疗仪治疗白癜风临床疗效显著、便于携带、操作方便、值得临床推广应用。

Objective To investigate the clinical efficacy of portable therapeutic ultraviolet （UV） instrument on the treatment of vitiligo. Methods A total of 68 patients with vitiligo were included in this study. All patients were randomly selected for treatment using UV instrument （ A, n = 34 ） and portable UV instrument （ B, n = 34）. Results The clinical efficacy in group A and B was 52.94% and 55.88% ,respectively. There was no significant difference between the two groups （ P 〉 0.05 ）. The significant difference for clinical efficacy in different body sites was also not observed between these two groups （ P 〉 0.05 ）. The therapeutic effect after four courses was significantly higher than that of two regimens （ P 〈 O. 05 ）. The pigmentation scoring after treatment was significantly increased in group A and B, compared pre-treatment（ P 〈 0. O1 ）. Conclusion Both UV instrument and portable therapeutic UV instrument showed effective in the treatment of vitiligo. The latter has the advantage of portable and eonventiable, making it more applicable in clinics.