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新型香草香料“K3”的GC/MS解析 被引量:11

Identification of the herbal spices “K3” by GC/MS
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摘要 目的对新型香草香料"K3"的主要化合物成分进行解析,为相关研究和应用提供参考。方法采用GC/MS方法,对新型香草香料"K3"样本进行检测,根据"K2"的主成分推断"K3"样本中检出的2种主要化合物成分的性质,并对其碎片离子图进行解析。结果初步推断香料"K3"中的化合物1为苯环上的2个氢被2个(-OCH3)基团取代的苯乙酰吲哚类化合物,分子式为C23H27NO3,分子量为365;化合物2为AM-2201(F代JWH-18),分子式为C24H22FNO,分子量为359。结论新型香草香料"K3"中含有合成大麻素类成分,该类药物应引起相关部门的重视。 Objective The main ingredients of "K3/SPICE" are analysed in the paper for the basis of further study. Methods The article analyses the " K3/SPICE" by GC/MS, and deduces the possible molecular structural formulas for the two main effective components of the " K3/SPICE" by both of the ingredients of "K2/SPICE" and the mass spectrum of "K3/SP1CE". Results As the result of the analysis, it is deduced that the compound 1 of "K3/SPICE" which is possible replaced 2-H in phenyl by 2-OCH3 is ranged synthetic phenylacetylindole cannabimimetic, and the compound 2 is AM-2201 which is fluoro-analog of JWH-018. Conclusion The "K3/SPICE" also has the ingredients of the types of synthetic cannabimimetie, and the species of herbal should be attracted the correlative govements attention..
出处 《中国法医学杂志》 CSCD 2014年第1期50-52,I0003,共4页 Chinese Journal of Forensic Medicine
关键词 法医毒物分析 合成大麻素 K3 GC MS 香料 forensic toxicological analysis synthetic cannabimimetic K3 GC/MS spice
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参考文献17

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二级参考文献5

  • 1Uchiyama N, Kikura-Hanajiri R, Ogata J, et al. Chemical analysis of synthetic cannabinoids as designer drugs in herbal products [J]. Forensic Sci Int, 2010, 198: 31-38.
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