正交试验优选复方沙棘和胃胶囊的提取工艺

Optimization of the extraction process for compound Shaji Hewei capsule by orthogonal test

目的:优化复方沙棘和胃胶囊的提取工艺。方法:以紫丁香苷含量和正丁醇浸出物为指标,采用L9(34)正交试验,优选最佳提取工艺条件。结果:影响提取工艺的因素依次为:提取次数>提取时间>加水量>浸泡时间。最佳工艺条件为:加10倍量水,提取2次,提取总时间4 h(2,2),浸泡时间40 min。结论:该工艺简便、可行,适合于工业生产。

Objective： To optimize the extraction procedure of compound Shaji Hewei capsule. Methods： extract was used as index, the optimum condition of the extraction were study by orthogonal test L9（34）. Results： The influencing effccts of factors were as follows： B 〉A〉 C 〉 D （A： extraction time, B： extraction times, C： liquid-solid ratio, D： soaking timc）.The optimal extraction condition were as follows： extract 4 h for two times, 10 times water, soaking 40 rain. Conclusion： The best extraction process is reasonable, practicable and convenient, and can be applied rightly in industry production.