摘要
AIM: To study the chemical constituents from the fermentation of the endophytic fungus HP-1 of Chinese eaglewood. METHODS: The chemical constituents were isolated by column chromatography on silica gel and Sephadex LH-20, and their structures were elucidated on the basis of spectroscopic analysis. RESULTS: Four compounds were isolated and identified as 3α, 3β, 10β-trimethyl-decahydroazuleno[6, 7]furan-8, 9, 14-triol(1), 4-hydroxyphenylacetic acid(2), 4-hydroxyphenethyl alcohol(3), and 5-hydroxymethyl-2-furancarboxaldehyde(4). CONCLUSION: Compound 1 was a new compound. Compound 2 showed antibacterial activity against Staphylococcus aureus.
AIM： To study the chemical constituents from the fermentation of the endophytic fimgus HP-1 of Chinese eaglewood. METHODS： The chemical constituents were isolated by column chromatography on silica gel and Sephadex LH-20, and their structures were elucidated on the basis of spectroscopic analysis. RESULTS： Four compounds were isolated and identified as 3a, 3,8, 10fl-trimethyl-decahydroazuleno[6, 7]furan-8, 9, 14-triol （1）, 4-hydroxyphenylacetic acid （2）, 4-hydroxyphenethyl alcohol （3）, and 5-hydroxymethyl-2-furancarboxaldehyde （4）. CONCLUSION： Compound 1 was a new compound. Compound 2 showed antibacterial activity against Staphylococcus aureus.
基金
supported by the Fundamental Research Funds for Central Public Welfare Research Institutes(Chinese Academy of Tropical Agricultural Sciences,No.1630052012014)
the National Nonprofit Institute Research Grant of CATAS-ITBB130404
