摘要
目的探讨解偶联蛋白P3(UCP3)基因IVS6g→a +1变异与中国汉族人肥胖及糖尿病的关系。 方法选取 30 6例无亲缘关系的中国人和 6 6例白种人 ,运用PCR -RFLP方法检测UCP3基因IVS6g→a +1的变异情况。 结果中国人与白种人中均未发现这种变异。 结论该基因变异不是中国汉族人肥胖与糖尿病发生的重要遗传因素。
Objective To investigatce the relationship between IVS6 g→a+1 variance of uncoupling protein 3 gene (UCP3) and obesity as well as diabetes in Chinese Hans. Methods The genotype of this variance was determined by the PCR-RFLP method in 306 unrelated Shanghai Chinese Hans and 66 normal Caucasians. Results No IVS6 g→a+1 variance of UCP3 gene was found in this group of Shanghai Chinese Hans and 66 Caucasians. Conclusion This variance of UCP3 gene is not a major predisposing genetic factor for obesity and diabetes in Chinese Hans.
出处
《上海第二医科大学学报》
CSCD
2001年第1期22-23,共2页
Acta Universitatis Medicinalis Secondae Shanghai
基金
国家自然科学基金资助项目!( 3 980 0 0 69)
