摘要
目的分析子宫平滑肌瘤细胞的DNA含量 ,并与同源的正常肌细胞相比较。 方法采用流式细胞术 (FCM)对 5 0例子宫肌瘤患者的肌瘤组织和正常肌组织进行DNA含量及细胞周期时相的测定。 结果子宫肌瘤组织的DNA指数 (DI)和正常肌组织的DI间无显著差异 (P >0 .0 5 ) ,但肌瘤组织的S期细胞的百分比 (SPF)和细胞分裂增殖指数 (PI)显著高于正常肌组织 (P <0 .0 5 ) ,肌瘤组织的SPF和PI与肌瘤的大小和患者的年龄无相关性。结论肌瘤组织的增殖活性高于正常肌组织。
Objective To investigate the differences of biological aggressiveness in terms of the DNA content and cell cycle between the leiomyoma and myometrium. Methods The cellular DNA content and cell cycle phase analysis by FCM were investigated in the leiomyoma and myometrium from 50 patients. Results No significant difference of DI was observed between the leiomyoma and myo metrium. The SPF and PI in the leiomyoma were more abundant than those in the myometrium (P<0.05),and were not correlated to the size of leiomyomas or the age of the patients. Conclusion Cell proliferation of the leiomyoma is higher than that of the myometrium.
出处
《上海第二医科大学学报》
CSCD
2001年第1期55-56,81,共3页
Acta Universitatis Medicinalis Secondae Shanghai
