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血管生成抑制素研究进展 被引量:1

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摘要 血管生成抑制素 (angiostatin ,AS)是近几年发现、命名的血管生成抑制因子 ,在肿瘤的治疗方面具有潜在的应用前景 ,对AS的研究已取得了较多成果 ,本文就AS在基础和临床前研究的最新近展作一综述。
出处 《国外医学(临床生物化学与检验学分册)》 2001年第1期14-15,共2页 Foreign Medical Sciences(section of Clinical Biochemistry and Laboratory Medicine
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同被引文献9

  • 1邱达泰,黄芝,欧阳高亮,鲍仕登.肿瘤血管生成促进因子和抑制因子[J].中国药物与临床,2005,5(7):485-488. 被引量:6
  • 2盛世乐,黄钢.VEGF上调survivin和bcl-2表达及抑制乳腺癌细胞凋亡的机制探讨[J].肿瘤,2005,25(6):525-529. 被引量:17
  • 3Bouvet M, Ellis LM, Nishizaki M, et al. Adenovirus-mediated wild-type p53 gene transfer down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human colon cancer. Cancer Res, 1998 ; 58 : 2288 - 2292
  • 4Zhang L, Yu D, Hu M, et al. Wild-type p53 suppresses angiogenesis in human leiomyosarcoma and synovial sarcoma by transcriptional suppression of vascular endothelial growth factor expression. Cancer Res,2000 ;60 : 3655 - 3661
  • 5O'Reilly MS, Holmgren L , Shing Y, et al. Angiostatin: an novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma. Cell, 1994; 79:315 -318
  • 6Katoh O,Takahashi T,Oguri T, et al. Vascular endothelial growth factor inhibits apoptotic death in hematopoietic cells after exposure to chemotherapeutic drugs by inducing MCL1 acting as an antiapoptotic factor. Cancer Res, 1998 ; 58:5565 - 5569
  • 7Pidgeon GP, Barr MP, Harmey JH, et al. Vascular endothelial growth factor (VEGF) upregulates BCL-2 and inhibits apoptosis in human and murine mammary adenocarcinoma cells. Br J Cancer, 2001 ; 85:273 -278
  • 8费嘉,张洹.血管内皮生长因子基因反义核酸的设计及其对K562细胞增殖的影响[J].中国病理生理杂志,2003,19(5):645-648. 被引量:11
  • 9陈德喜,王申五,曹国栋,马丽萍,潘秀英.转导野生型p53的K562细胞出现生长抑制和凋亡[J].中国实验血液学杂志,1998,6(3):224-226. 被引量:3

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