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环境因素诱导细菌致病基因的表达及其调节 被引量：1

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摘要 研究细菌致病基因的表达及其调节特性 ,有助于定义潜在的毒力因子 ,鉴定新的致病基因和毒力因子。本文综述了特定的宿主产物、温度、Fe离子浓度、渗透压等环境信号诱导细菌致病基因表达的机理 ,以及两成分调节系统和DNA超螺旋的改变对细菌致病基因表达的调节。
作者 黄彬 尹一兵 俞纯山
机构地区 中山医科大学附属第一医院检验科 重庆医科大学医学检验系
出处 《国外医学（临床生物化学与检验学分册）》 2001年第1期28-29,共2页 Foreign Medical Sciences(section of Clinical Biochemistry and Laboratory Medicine
关键词 细菌 致病基因 环境因素 基因表达 调节
分类号 R378 [医药卫生—病原生物学]
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参考文献10

  • 1Kroll JS.Bacterial virulence: an environmental response[].Archives of Disease in Childhood.1991
  • 2Jungnitz H,West NP,Walker MJ,et al.A second two-component regulatory system of Bordetella bronchiseptica reqquired for bacterial resistance to oxidative stress, production of acid phosphatase, and in vivo persistence[].Infection and Immunity.1998
  • 3Gunn JS,Belden WJ,Miller SI.Identification of Phop-PhoQ activated genes within a duplicated region of the Salmonella typhimurium chromosome[].Microbial Pathogenesis.1998
  • 4Ankenbauer RG,Nester EW.Sugar-mediated induction of Agrobacterium tumefaciens virulence genes: structural specificity and activities of monosaccharides[].Journal of Bacteriology.1990
  • 5Dorman CJ.DNA supercoiling and environmental regulation of gene expressionin pathogenic bacteria[].Infection and Immunity.1991
  • 6Calderwood SB,Mekalanos JJ.Iron regulation of Shiga-like toxin expression in Escherichia coli is mediated by the fur locus[].Journal of Bacteriology.1987
  • 7Mekalanos JJ.Environmental signals controling expression of virulence determinants in bacteria[].Journal of Bacteriology.1992
  • 8Hale TL.Genetic basis of virulence in Shigella species[].Microbiological Reviews.1991
  • 9Dirita VJ,Parsot C,Jander G,et al.Regulatory cascade controls virulence in vibrio cholerae[].Proceedings of the National Academy of Sciences of the United States of America.1991
  • 10Bernardini ML,Fontaine A,Sansonnetti PJ.The two-component regulatory system ompR-envZ controls the virulence of Shigella flexneri[].Journal of Bacteriology.1990

同被引文献13

  • 1Shea R J, Mulks M H. ohr, encoding an organic hydroperoxide reductase, Is an in vivo-induced gene in Actinobacillus pleuropneumoniae [J]. Infect Immun, 2002,70(2) : 794.
  • 2Lesniak J, Barton W A, Nikolov D B. Structural and functional characterization of the Pseudomonas hydroperozide resistance protein ohr[J]. Embo J, 2002, 21(24) : 6649-6659.
  • 3Manchado M, Michan C, Pueyo C. Hydrogen peroxide activates the SoxRS regulon in vivo [J]. J Bacteriol,2000,182:6842-6844.
  • 4Storz G, Toledano M B. Regulation of bacterial gene expression in response to oxidative stress[J]. Methods Enzymol, 1994,236 : 196-207.
  • 5Rosner J L,Storz G. Regulation of bacterial responses to oxidative stress[J]. Cell Regul, 1997,35 : 163-177.
  • 6Fuangthong M, Atichartpongkul S, Mongkolsuk S, et al. OhrR is a repressor of ohrA, a key organic hydroperoxide resistance determinant in Bacillus subtilis [J]. J Bacteriol, 2001,183 : 4134-4141.
  • 7Bsat N, Herbig A, Casillas-Martinez L, et al. Bacillus subtilis contains multiple Fur homologues: identification of the iron uptake (Fur) and peroxide regulon (PerR) repressors [J]. Mol Microbiol, 1998,29 : 189- 198.
  • 8Sukchawalit R, Loprasert S, Atichartpongkul S, et al. Complex regulation of the organic hydroperoxide resistance gene (ohr) from Xanthomonas involves OhrR,a novel peroxide-inducible negative regulator, and posttranscriptional modifications[J]. J Bacteriol, 2001,183 : 4405-4412.
  • 9Ochsner U A, Hassett D J, Vasil. M L. Genetic and physiological characterization of ohr, encoding a protein involved in organic hydroperoxide resistance in Pseudomonas aeruginosa [J]. J Bacteriol, 2001,183, 773-778.
  • 10Rince A,Giard J,Pichereau V, et al. Identification and characterization of gsp65, an organic hydroperoxide resistance (ohr) gene encoding a general stress protein in Enterococcus faecalis [J]. J Bacteriol, 2001, 183:1482-1488.

引证文献1

国外医学（临床生物化学与检验学分册）
2001年 第1期

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