急性心肌梗死患者QTV及HRV与室性心律失常的相关性

Relationship of QTV and HRV with ventricular arrhythmias in AMI

目的分析AMI患者QTV及HRV与室性心律失常的关系。方法比较27例急性心肌梗死患者和30例健康对照组24h动态心电图,分析心肌梗死组和健康对照组心率变异性、QT变异度、QT变异系数等。结果健康对照组QT间期与心率呈直线相关(r=-0.822,P<0.01);急性心肌梗死组QT间期与心率呈直线相关(r=-0.891,P<0.01)。SDNN与心肌梗死严重程度具有相关性(r=-0.511,P<0.01);QTV与心肌梗死严重程度具有相关性(r=-0.613,P<0.01);QTCV与心肌梗死严重程度具有相关性(r=-0.648,P<0.01)。结论急性心肌梗死患者平均心率、QTV、QT间期、SDNN均发生变化,对预测室性心律失常及猝死的发生可能具有重要临床意义。

Objective To discuss the relationship of QTV and HRV with ventricular arrhythmias in AMI. Methods Twenty-seven cases with AMI and thirty healthy control group were compared in 24 hours dynamic electrocardiogram. HRV, QTV, QTCV were compared between two groups. Results QT interval of healthy control group showed correlation with HR （r=-0.822, P 〈 0.01）. QT interval of AMI group showed correlation with HR （r=-0.891, P 〈 0.01）. SDNN, QTV and QTCVshowed correlation with severity of myocardial infarction （r=-0.511, P 〈 0.01; r=-0.613, P 〈 0.01; r=- 0.648, P 〈 0.01）. Conclusion HR, QTV, QT, SDNN change in AMI, which show clinical significance in foretelling ventricular arrhythmias and sudden death.