雷贝拉唑与奥美拉唑治疗胃食管反流病80例临床疗效分析

Curative effect analysis of rabeprazole and omeprazole on 80 patients with gastroesophageal reflux disease

目的探讨胃食管反流病临床特点及有效治疗方法。方法对照组给予奥美拉唑治疗;研究组给予雷贝拉唑治疗。结果研究组总有效率90.00%,对照组总有效率75.00%,两组患者疗效比较具有统计学意义;不良反应发生率研究组为7.50%,对照组为10.00%,均为胀气或腹泻,经对症治疗后症状消失。结论应根据患者综合情况进行判断,确定适当治疗方案,达到更好的治疗效果。

Objective To study the clinical characteristics and effective treatment method of gastroesophageal reflux disease. Methods The patients in control group were treated with omeprazole, while the patients in research group were treated with rabeprazole. Results The total effective rate of research group was 90.00%, while the control group was 75.00%, there were significant differences between the two groups （P〈0.05） ; incidence of adverse reactions of research group was 7.50%, while the control group was 10.00%, the patients of two groups had the same adverse reactions, flatulence or diarrhea, and the symptoms disappeared after symptomatic treatment, there was no significant difference between the two groups （P〉0.05）. Conclusion Physicians should make judgment according to the comprehensive situation, determine the appropriate treatment plan, in order to achieve more effective therapeutic effect.