胃癌患者手术治疗效果及影响因素分析

Analysis of effect of surgical treatment and influencing factors in patients with gastric cancer

目的 探讨胃癌患者手术治疗效果及影响因素.方法选取本院2009年1月～2010年1月收治的胃癌152例患者进行回顾性分析.结果 152例患者预后满意65例,症状显著改善42例,良好28例,有17例较差.手术总有效率为88.82%（135/152）.且152例患者经手术治疗后,其1年和3年的生存率分别为86.18%（131/152）和66.45%（101/152）.多因素Logistic回归分析发现,Borrmann分型、胃癌组织学类型、胃癌肿瘤所处部位、胃癌肿瘤大小、肿瘤浸润程度和淋巴结转移度、手术根治程度和术后化疗为影响胃癌患者治疗的效果的独立危险因素（P ＜ 0.05）.结论影响胃癌术后预后的因素较多,临床需要根据患者的自身因素和病情选择恰当的治疗方式来改善患者的生活质量.

Objective To investigate the effect of surgical treatment and influencing factors in patients with gastric cancer. Methods A total of 152 patients with gastric cancer in our hospital from January 2009 to January 2010 were retrospectively analyzed. Results In 152 patients, there were 65 cases with satisfactory prognosis, 42 cases with symptoms improved significantly, 28 cases with good effect and 17 cases poorer. The total efficiency of operation was 88.82% （135/152）. And after the operation treatment, the 1 year and 3 years survival rate of 152 patients were 86.18% （131/152） and 66.45% （101/152） respectively. The multivariate logistic regression analysis showed that the Borrmann type, histologic type, tumor position, tumor size, degree of tumor invasion and lymph node metastasis, degree of radical operation and postoperative chemotherapy were independent risk factors influencing the treatment effect of patients with gastric cancer （P 〈 0.05）. Conclusion There are many factors influencing the prognosis of gastric cancer after the operation, the appropriate treatment method is chose according to the patient＇s own factors and disease to improve the quality of life of patients.