孕妇牙周病的流行病学调查及相关治疗对妊娠结局的影响

Effects of maternal periodontal disease epidemiology and related treatment on pregnancy outcome

目的调查我院孕妇口腔情况并探讨口腔治疗对妊娠结局的影响。方法随机在我院选择10 000例建卡产检的孕中期妇女,调查孕妇的牙周病变情况,患病者则根据其治疗依从性分为两组,治疗组4 934例,接受治疗及护理;常规组患者2 859例,不接受医院的治疗;未患病者为对照组,观察患者妊娠期流产、早产及低出生体重儿的发生率;检测患者唾液内IL-1β、IL-6、弹性蛋白酶(EA),确定影响妊娠结局的原因。结果孕妇中77.93%可发生牙周病变,经过治疗和护理后妊娠结局较其他组好,且患者与正常孕妇中的IL-1β、IL-6、EA存在明显差异,具有显著意义(P<0.05)。结论孕妇的牙周病变发生率高,且牙周病变可影响妊娠结局,经过治疗后明显改善妊娠结局,减少早产儿及低出生体重儿的发生率。

Objective To investigate the oral cavity of pregnant women and to investigate the effects of oral treatment on pregnancy outcome. Methods Chose 10 000 cases for check cards to build the second trimester pregnant women, the women was divided into two treatment groups based on their compliance the group of treatment had 4934 cases, treatment and care; routine 2 859 cases of patients not receiving treatment hospitals; unaffected by the control group, the incidence was observed in patients with pregnancy miscarriage, premature delivery and low birth weight children. The patient＇s saliva to detect IL-1β, IL-6, elastase （EA）, to determine the factors affecting the outcome of pregnancy. Results The 77.93% of pregnant women had gum disease, but the pregnancy outcomes was better than other groups after treatment and care, and patients with normal pregnant women IL-1β, IL-6, EA significantly different with a statistically significant （P 〈0.05）. Conclusion The high incidence of maternal periodontal and gum disease may affect pregnancy outcomes, improve significantly after treatment pregnancy outcomes, reduce the incidence of low birth weight preterm children and children＇s.