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格列美脲联合胰岛素治疗肥胖型2型糖尿病 被引量:3

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摘要 2型糖尿病发病的2个重要因素是胰岛细胞功能缺陷和胰岛素抵抗.随病程延长,胰岛细胞功能逐渐衰竭,多数患者需应用胰岛素治疗.肥胖型2型糖尿病患者存在胰岛细胞功能减退的同时存在胰岛素抵抗,治疗过程中血糖控制难度大,胰岛素用量大.格列美脲(商品名:亚莫利)是第3代磺脲类口服药,除具有胰岛素促泌作用外,尚具有显著的外周胰岛素增敏作用,是美国食品与药品管理局推荐的唯一可与胰岛素联用的磺脲制剂.本研究旨在观察肥胖型2型糖尿病患者在胰岛素治疗的基础上加用格列美脲的临床疗效.
机构地区 解放军
出处 《实用医药杂志》 2014年第2期125-126,共2页 Practical Journal of Medicine & Pharmacy
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