高血压脑出血与血浆同型半胱氨酸相关

The relationship of the plasma homocysteine levels in patients with hypertension cerebral hemorrhage

目的:探讨血浆同型半胱氨酸(Hcy)与高血压脑出血的关系。方法:选择我院神经内科住院确诊为高血压脑出血患者100例为高血压脑出血组,同时选择100例健康体检者为健康组,比较两组血浆Hcy水平;将100例高血压脑出血患者按血浆Hcy水平分为高Hcy组和正常Hcy组,比较两组治疗后神经功能(CSS)恢复状况。结果:高血压脑出血者血浆Hcy水平显著高于健康体检者,两组比较差异有统计学意义(P<0.01);经治疗后高Hcy者神经功能恢复比正常Hcy者差,两组比较差异有统计学意义(P<0.01)。结论:血浆Hcy水平与高血压脑出血的发病密切相关,临床上可通过检测血浆Hcy水平判断高血压脑出血患者病情的轻重及预后。

Objective： To investigate the correlation of plasma homocysteine （Hey） with hypertensive cerebral hemorrhage. Methods： 100 patients diagnosed with hypertensive cerebral hemorrhage and admitted into our department were selected as the hypertensive cerebral hemorrhage group, while another 100 cases of healthy check-up persons as the control group. The Hcy levels of the subjects in both groups were were divided into compared. Meanwhile, 100 cases in the hypertensive cerebral hemorrhage group the high Hcy group and the normal Hcy group based on the Hcy levels, and their neurologic function recovery were compared sults： The plasma Hey level of the patients by Chinese stroke scale （CSS） after treatment. Rewith hypertension cerebral hemorrhage were higher than that of the healthy controls, which was of statistical significance （P〈0. 01） the neurologic function recovery of the high Hey group after treatment was worse than that of the low Hey group, which was of statistical difference （P〈0.01）. Conclusion： Plasma Hey levels are closely associated with the onset of hypertension cerebral hemorrhage, and the clinical detection of plasma Hcy levels can determine the severity and prognosis of patients with hypertension cerebral hemorrhage.