昆虫热激蛋白90的研究进展

Research Progress on Heat Shock Protein 90 of Insects

热激蛋白90(Heat shock protein 90,Hsp90)是细胞内最为广泛的分子伴侣之一,间接调控细胞内多条与细胞增殖、分化、存活、滞育以及与凋亡相关的信号转导通路。近年来,对Hsp90家族成员在分子水平上的认识不断深入,Hsp90已成为细胞免疫、信号转导以及抗肿瘤研究的前沿课题。昆虫功能基因组的研究正在世界范围内掀起热潮,与昆虫滞育相关热激蛋白的研究也不断深入。对近年来国内外Hsp90的生物学特性、生物学功能及其在昆虫防治中的研究现状及前景进行综述,以期为害虫综合防治的研究提供参考信息。

Heat shock protein 90（Hsp90）is one of the most extensive molecular chaperones in cells, indirect regulation of intracellular multiple and cell proliferation, differentiation, and survival, diapause, apoptosis and related signal transduction pathway. In recent years, awareness of Hsp90 family members at the molecular level, Hsp90 has become immune cells, signal transduction and anti-tumor research frontiers. Insects functional genome research is a worldwide craze, heat shock protein related to insect diapause research also unceasingly thorough. This article summarized the biological characteristics of Hsp90 at home and abroad in recent years, the biological function of Hsp90 and its control research present situation and prospect in insect, in order to provide references information for the research of integrated pest control.