肝硬化食管静脉曲张破裂出血危险因素分析

A retrospective analysis of the main risk factors and protective factors of esophageal variceal bleeding in liver cirrhosis

目的探究导致肝硬化食管静脉曲张破裂出血的危险因素，用于肝硬化食管静脉曲张破裂出血的早期风险评估。方法将161例肝硬化食管静脉曲张患者分为出血组（101例）和非出血组（60例），比较两组间29个临床指标，进行单因素分析及非条件Logistic回归分析。结果经单因素分级及非条件Logistic回归分析，白细胞计数、血小板计数（负相关）、凝血酶原时间及门脉内径比较差异均有统计学意义。结论白细胞计数、血小板计数、凝血酶原时间及门静脉内径对肝硬化食管静脉曲张破裂出血的发生有预测意义，其中血小板计数与其发生呈负相关。

To identify the main risk factors and protective factors of esophageal variceal bleeding（EVB） in liver cirrhosis in order to early evaluate the risk of EVB in liver cirrhosis Methods was made A retrospective analysis of 161 hospitalized patients with liver cirrhosis and esophageal They were divided into two groups, the hemorrhage group（ 101 cases） and non bleeding varices one（60 cases）. A total of 29 indicators were compared between the two groups, and all the variables were examined by univariate analysis and Logistic regression procedures, to verify the major risk factors of EVB with cirrhosis. Results WBC, PC, PT and diameter of the portal vein had significant differences between the two groups. Conclusions WBC, PT and diameter of the portal vein are positively correlated with EVB in liver cirrhosis, and PC is nega-tively correlated with EVB.