总血红蛋白、碳氧血红蛋白、高铁血红蛋白浓度无创连续监测的现状

术中及时发现贫血，确定一氧化碳中毒者碳氧血红蛋白的浓度，调整药物剂量以防止高铁血红蛋白浓度超过中毒水平都很重要。脉搏氧饱和度仪的工作原理是发射光到组织并测定被组织吸收的光量。实验室氧血红蛋白计也利用同样的原理检测血红蛋白浓度。这两种仪器的工作原理相同，脉搏氧饱和度仪经过改造也可用于监测血红蛋白浓度。目前市场上有两种脉搏氧饱和度仪，MasimoRainbowSETandOrSenseNBM-200MP，都可以同时检测总血红蛋白浓度，Masimo还能检测高铁血红蛋白和碳氧血红蛋白。本文旨在就有关同行对这些仪器准确性的评议文献进行综述。

Intraoperative early detection of anemia, identifying toxic levels of carboxyhemoglobin after carbon monoxide exposure and titrating drug dosage to prevent toxic levels of methemoglobin are important goals. The pulse oximeter works by illuminating light into the tissue and sensing the amount of light absorbed. The same methodology is used by laboratory hemoglobinometers to measure hemoglobin concentration. Because both devices work in the same way, efforts were made to modify the pulse oximeter to also measure hemoglobin concentration. Currently there are 2 commercial pulse oximeters （Masimo Rainbow SET and OrSense NBM-200MP） that measure total hemoglobin concentration and one （Masimo） that also measures methemoglobin and carboxyhemoglobin. In this review, we describe the peer-reviewed literature addressing the accuracy of these monitors.