葡萄糖胰岛素在预防剖宫产腹部切口脂肪液化中的价值

Value of glucose-insulin in preventing fat liquefaction of abdominal incision after cesarean

目的：探索预防剖宫产腹部切1：3脂肪液化的方法。方法：选取2011年10月-2013年10月于本院住院择期剖宫产的产妇100例分为实验组和对照组各50例，两组均采用下腹正中纵切口，腹壁脂肪均厚3～5cm，采用强生公司4／0薇乔线皮内缝合皮肤。观察组每天常规换药，并分别于术后第2、4天在患者腹部切口中段两侧旁开3cm部位的脂肪层内各注入10％葡萄糖5ml加胰岛素4单位混合液；对照组每天常规换药。结果：实验组脂肪液化0例，对照组6例，两组差异有统计学意义（P〈0．05）；伤口感染实验组1例，对照组2例，两组差异无统计学意义（P〉0．05）。结论：剖宫产术后腹部切口脂肪层注射10％葡萄糖加胰岛素混合液能有效地预防腹部切口脂肪液化。

Objective： To explore the methods of prevention for fat liquefaction of abdominal incision after cesarean. Methods： 100 patients after elective cesarean section from October 2011 to October 2013 in our hospital were divided into two groups, 50 cases in ex- perimental group and 50 cases in control group , both groups were operated on a ventral midline longitudinal incision by 4/0 Vicryl （ Johnson corporation ） suture skin buried seam line , the thickness of abdominal fat were 3 cm - 5 cm. Experimental group ： daily dressing , and injection of 5 ml 10% glucose plus four units insulin in both sides of fat layer on the site 3 cm of abdominal incision 2 d , 4 d after opera- tion, respectively. Control group： daily routine dressing. Results： 0 case fat liquefaction in experimental group, 6 cases in control group; 1 case wound infection in experimental group and 2 cases in control group, there was significant difference in fat liquefaction between the two groups, and there was no significant difference in wound infection between the two groups. Conclusion： Injection of 10 % glucose plus insu- lin in fat layer beyond 3 cm of abdominal incision can be an effective prevention for fat liquefaction of abdominal incision.