尿路感染病原菌分布及耐药分析

Distribution and drug resistance analysis of pathogenic bacteria of urinary tract infection

目的研究福州地区尿路感染病原菌的分布及耐药情况。方法2013年1～12月，共收集2958株尿路感染病原菌进行鉴定和药敏试验。结果2958株病原菌中前4位依次是大肠埃希菌、真菌、粪肠球菌和肺炎克雷伯菌。大肠埃希菌耐药率最高的抗生素是氨苄西林，而对氨苄西林／舒巴坦复合剂的耐药率明显低于对前者的耐药率（P〈0．05）；对阿米卡星的耐药率也明显低于庆大霉素（P〈0．05）。结论大肠埃希菌仍是尿路感染的主要病原菌，应根据细菌的药敏试验结果使用抗生素。

Objective To study distribution of drug resistance pathogenic bacteria of urinary tract infection in Fuzhou. Methods 2958 strains of pathogenic bacteria of urinary tract infection were collected and identified and given drug sensitive test from January to December 2013. Results Among 2958 strains of pathogenic bacteria,the top 4 were Es- cherichia eoli,fungi,Enteroeoccus faecalis and Klebsiella pnenmoniae Respectively.Antibiotics having the highest rate of drug resistance to Escherichia coli was ampicillin,the dnlg resistance rate to ampicillin/sulbactam compound was obvi- ously than that of ampicillin （P〈0.05）;the drug resistance rate to amikacin was obviously than that of gentamicin （P〈 0.05）. Conclusion Eseherichia coli is main pathogenic bacteria of urinary tract infection and the use of antibiotics should be based on the results of drug sensitive test of bacteria.