血乳酸水平与危重症患者预后的相关性分析

Correlation analysis of serum lactic acid level with prognosis of critical patient

目的观察乳酸水平与危重症患者预后的相关性,为危重症患者的治疗提供理论依据。方法通过对82例危重症患者血乳酸水平的动态监测,比较死亡组患者和存活组患者乳酸水平及不同乳酸水平患者不良预后的情况。结果严重乳酸中毒组患者的乳酸峰值、APACHEⅡ、休克、多器官功能障碍综合征、死亡比例明显高于其他两组;入院后乳酸水平及入院6、12、24 h后乳酸水平,死亡组均明显高于存活组患者,差异有统计学意义(P<0.01),经过Spearman相关性分析,入院乳酸水平与APACHEⅡ评分具有显著的正相关关系(P<0.01)。结论血乳酸水平可作为判断危重症患者病情和预后的重要监测指标。

Objective To observe the relationship of serum lactic acid level with prognosis of critical patient dynamically for providing theoretical basis for the treatment of critical patient. Methods The serum lactic acid level of 82 cases of critical patients were monitored dynamically,the levels of serum lactic acid in the death group and survival group were compared and the bad prognosis in the different serum lactic acid level of patients. Results The peak value of lactic acid,APACHEⅡ,shock,MODS and the percentage of death in the sever lactic acidosis group were all higher than those in the other two groups.The level of lactic acid at the time of on admission,6 h,12 h and 24 h after admission in the death group were all higher than those in the survival group.All these differences had significantly statistical significance（P 0.01）.The level of lactic acid at the time of on admission had significant positive relationship with after Spearman correlation analysis（P0.01）. Conclusion The level of serum lactic acid can be selected as one important index of monitoring condition and prognosis of critical patients.