儿童腺病毒感染125例临床诊治分析

Analysis of clinical diagnosis and treatment of children adenovirus infection

目的分析儿童腺病毒(ADV)感染的临床特点,为临床诊断和治疗提供参考。方法选取本院呼吸道ADV感染患儿125例,经ELISA检测血清ADV-IgM(+),确诊为ADV感染,给予抗感染及对症治疗,并对临床资料进行回顾性分析。结果儿童呼吸道ADV感染发病高峰在冬、春季;婴幼儿发病率较高,<3岁者占84.8%。经积极抗感染及对症治疗后,119例临床治愈出院,6例好转出院。出院随访3个月,均未见后遗症发生。结论儿童腺病毒感染婴幼儿多见,易侵犯呼吸系统,合并多脏器损害及细菌感染,其临床表现多样化,重症病例少见,值得临床关注。

Objective To analyze the clinical feature of children adenovirus（ADV） infection and provide references for clinical diagnosis and treatment.Methods 125 cases of children with respiratory ADV infection were selected and confirmed to be infected with ADV according to ELISA serum test showing ADV-IgM（＋）.They were all given anti-infectious and symptomatic treatment.The clinical data were analyzed retrospectively.Results The peak period of child respiratory ADV infection was in winter and spring; the incidence rate of infants was relatively high, up to 84.8% in children less than 3 years old. After active anti-infectious and symptomatic treatment,119 patients recovered and discharged from the hospital,and 6 cases became better and discharged from the hospital.According to the three-month post-discharge follow-up, no sequela was detected.Conclusion Children ADV infection is common in infants, which is easy to attack respiratory system and complicated with multiple organ dysfunction and bacterial infection.In recent years, the infection has shown diverse clinical manifestations and rare severe cases, which is worthy of clinical attention.