T_(3-4)N_(0-2)M_0近端胃癌胃裸区清扫加D_2根治术30例疗效观察

Curative effect research of T_(3-4)N_(0-2)M_0 distal gastric cancer after D_2 opration combining with stomach bare area cleaning

目的观察胃裸区清扫加D2根治术治疗T3-4N0-2M0近端胃癌的疗效。方法将同期收治的60例T3-4N0-2M0胃癌患者随机分为观察组(A组)和对照组(B组)各30例,观察组行D2根治术+胃裸区清扫、对照组行D2根治术,观察两组患者总有效率、术后五年生存率、围手术期并发症、术后消化系并发症及Spitzer生存质量评分等指标。结果A组患者治疗后较B组患者Spitzer生存评分远期改善明显,差异有统计学意义(P<0.05);其治疗后总有效率、术后五年生存率明显高于B组,差异有统计学意义(P<0.05);其肿瘤术后复发率明显低于B组,差异有统计学意义(P<0.05);不良反应发生率未明显增加(P>0.05)。结论胃裸区清扫加D2根治术治疗近端胃癌疗效确切,值得推广应用。

Objective Observing the curative effect of T3-4 N 0-2 M 0 distal gastric cancer after D2 opration combining with stomach bare area cleaning. Methods Randomly choosing 60 T3-4 N0-2 M0 distal gastric cancer patients, randomly dividing into two groups equally （A group and B group） ;A group adopted D 2 opration combining with stomach bare area cleaning, B group adopted D 20pration ; observing the effective, 5year survival rate after opration, perioperative complications, postoperative complications, Spitzer score. Results Spitzer score of A group is better than B group （ P 〈 0.05 ） ; the total effective rate,5 year survival rate and perioperative complications are better than B group（ P 〈 0. 05 ） ; postoperative complications has no defferent（ P 〉 0.05 ）. Conclusion That D 2opration combining with stomach bare area cleaning treating T3-4 N0-2 M 0 distal gastric cancer was worthy to be popularized.