摘要
目的 探讨补充壳聚糖对不同负荷运动大鼠骨骼肌自由基代谢的影响。方法 以 SD大鼠为实验对象，随机分成壳聚糖服用组和对照组。每大组群又分成安静组、一次性有氧运动组、一次性大强度运动组和连续运动组。处死后，测定比目鱼肌和腓肠肌的 SOD(超氧化物岐化酶 )MAD丙二醛。结果 1.比目鱼肌和腓肠在一次性有氧运动后即刻和一次性大强度运动后即刻， MDA值均较安静对照组有显著性升高 (P < 0.01)。 2.腓肠肌的脂质过氧化反应程度明显高于比目鱼肌；腓肠肌的 MDA与安静对照组相比高出 85.7％ (P< 0.01)。 3.连续运动＋服壳聚糖组的 MDA显著下降。结论 1.脂质过氧化加强，与运动强度有关。 SOD活性相对下降可能是运动后骨骼肌细胞脂质过氧化加强的原因之一。 2.不同骨骼肌脂质过氧化水平是不同的。 3.随着运动负荷加大，壳聚糖消除体内自由基的作用越明显。
objective this study was to determine the effects of taking chitson and different loads eccentric contracting exercise on free radicals mitabolism of skeletal muscle in rats.Methods 62 Sprage－ Dawiey rats were randomly awwigned to take chitson group and not take chitson group.Each group adn endurance torining group.All the rats in exercise immediately,and the rats in control group were killed at the same time.The testing indexes included the skeletal muscle SOD,MDA.Results 1.The MDA values of soleus muscle and gastrocnemius muscle increased 11.5％ and 142.(P< 0.01)after one bout anaerobic exercise.2.the skeletal muscles SOD values didnt change significantly.3.Rats gastrocmemius muscle had a higher lever of free radicals merabolism compared with soleus muscle aftrt one bout artobic exercise.And gastrocnemius muscles MDA values were still higher than contril groups about 87.5％ after being trained ten days.Conclusion The trained rats which took Chitson had a better on antioxidant compared with the without training.
出处
《现代康复》
CSCD
2001年第2期138-139,共2页
Modern Rehabilitation
