还元注射液对出血性脑卒中患者肿瘤坏死因子-α可溶性白介素-2受体的影响

Studies of Huanyuan injection on TNF－α and sIL－ 2R in patients with acute hemorrhage stroke

目的 观察还元注射液对急性出血性脑卒中患者肿瘤坏死因子－α (TNF－α )、可溶性白介素－ 2受体 (sIL－ 2R)的影响。方法 急性出血性脑卒中患者 60例，随机分为还元液治疗组和甘露醇治疗对照组。观察给药前后临床神经功能缺损积分、 CT、 TNF－α和 sIL－ 2R等参数的变化。结果 出血性脑卒中患者自体脑出血模型动物血中 TNF－α、 sIL－ 2R明显上升，还元液可在一定程度上抑制这种改变。结论 还元注射液对急性出血性脑卒中患者 TNF－α、 sIL－ 2R的影响可能是其治疗作用机理之一。

Objective To observe the effect of Huanyuan Injection on TNF－α、 sIL－ 2R in patients with acute Intracranial hemorrhage.Method Sixty patients were randomly selected and divided into two groups.TNF－α、 sIL－ 2R in the blood of the patients were observed before and after therapy with Huanyuan Injection.Result Increasing level of TNF－α、 sIL－ 2R could be detected,at the same time,Huayuan Injection could react on the differentiation.Conclusion The effect of Hyanyuan Injection on the levels of TNF－α、 sIL－ 2R may show some insight on its therapeutic mechanism for acute hemorrhage stroke.