冠心病患者慢性肺炎衣原体感染与年龄的关系

The relation between chronic chlamydia pneumoniae infection and the ages of coronary heart disease patients

目的 :探讨冠心病 (CHD)患者慢性肺炎衣原体 (CP)感染与年龄的关系 ,以进一步了解慢性 CP感染在 CHD发病中的作用。方法 :采用微量免疫荧光法测定 130例不同年龄段 CHD患者血清中 CP特异性 Ig G抗体滴度 ,进行统计学分析。结果 :随着年龄的增长 ,CP感染率明显增加 ,且其平均抗体滴度也随年龄增加而升高 (P<0 .0 5 )。结论 :慢性 CP感染与年龄有关 ,慢性 CP感染可能在老年 CHD患者的发病中起一定作用。

Objective:To investigate the relation between chronic chlamydia pneumoniae (CP) infection and ages of coronary heart disease(CHD) patients,in order to further understand the mechanisms of chronic CP infection on the developing of CHD.Method:CP specific IgG titers were measured in 130 CHD patients at different ages using microimmun fluoroassay.Result:Infection rate and mean IgG titer were significantly higher in the elder CHD group(P< 0.05 ).Conclusion:The elder CHD patients were susceptible to chronic CP infection, which was considered to be related to CHD. So chronic CP infection may play a role in the developing of CHD in elder patients.