心舒口服液对麻醉犬心脏血流动力学的影响

The Effects of XINSHU Oral Liquid on Hemodynamics and Oxygen Consumption of Myocardium in Dog Hearts

目的 探讨心舒口服液对心脏功能的药理作用机理。方法 采用麻醉犬冠脉血流量 ,左室作功能力和心肌耗氧量等指标的变化 ,研究心舒口服液对心肌作用机理。结果 心舒口服液可以明显增加冠脉血流量 ,改善心肌收缩功能。结论 心舒口服液对心脏功能有明显调节和改善作用 ,为进一步临床研究提供实验依据。

Aim To investigate the pharmacological action mechanisms of XINSHU oral liquid on heart functions in dog.Methods The varieties of the following parameters were used to study its action mechanisms on myocardium,such as coronary blood flow,the work ability of left ventricular and myocardial oxygen consumption of normal anaesthetic dogs.Results XINSHU oral liqrid could enhance coronary blood flow and improve the myocardial systolic functions significantly.Conclusion It shows that the heart functions of dogs could be adjusted and improved by XINSHU oral liquid,which would provide experimental grounds for further clinical study.