老年离退休人群血浆Hcy水平检测及与心血管疾病传统危险因素的相关分析

The Related Analysis between Plasma Hcy Level Detection and Traditional Risk Factors of Cardiovascular Disease with Retired People

目的:探讨某地区离退休人群血浆中同型半胱氨酸(Hcy)水平的变化,探讨高Hcy血症与心血管疾病传统危险因素的关系,为老年人群健康体检预防心血管疾病提供理论依据和指导。方法:收集2013年十堰市地区东风公司离退休职工2200例血浆Hcy检测结果,按年龄与性别做分组统计。选取高Hcy血症人群分为高血压组、心电图异常改变组、吸烟组、高脂血症组、高血糖组。结果:本次老年体检人群高Hcy血症312例,占本次体检人群的14.18%,不同年龄组不同性别间的Hcy水平比较差异无统计学意义(P>0.05);高血压组、心电图异常改变组、高脂血症组、高血糖组Hcy平均水平均高于健康对照组,差异有统计学意义(P<0.05);高Hcy血症在高血压组发生率最高,其次为心电图异常改变组。结论:老年人群中高Hcy血症与心血管传统危险因素呈正相关,在健康体检中定期检测Hcy,对干预治疗老年人群心血管疾病有积极作用。

Objective：To discusses plasma homocysteine（Hcy）levels in the change of retired people of a region,to discusses the relationship between high Hcy levels and traditional risk factors of cardiovascular disease,provide theoretical basis and guidance,to prevent cardiovascular disease for elderly health check-up.Method：2200 cases of plasma Hcy results of retired worker of Shiyan dongfeng company in 2013 were grouped by age and gender did statistics;Selected high Hcy levels crowd were divided into high blood pressure,electrocardiogram（ecg）abnormal change,smoking,hyperlipidemia, hyperglycemia group.Result：312 cases of high Hcy levels of elderly check-up crowd,which accounted for 14.18%;The average Hcy levels between different age groups and different gender were no statistical significance（P＆gt;0.05）;The average Hcy levels of high blood pressure,electrocardiogram（ecg） abnormal change group,hyperlipidemia,hyperglycemia group are higher than the healthy controls,the difference were statistically significant（P＆lt;0.05）;The highest incidence of High Hcy levels was in hypertension group,followed by abnormal changes of electrocardiogram（ecg）group.Conclusion：High Hcy levels of the elderly and traditional cardiovascular risk factors are positively correlated,Hcy in healthy check-up regularly detection,produce positive effects on intervention in the treatment of elderly cardiovascular disease.